GAPIII and Containment Certification Scheme
The WHO Global Action Plan (GAPIII) was endorsed by the WHO Strategic Advisory Group of Experts on Immunization in October 2014 and the World Health Assembly resolution WHA68.3 in May 2015. The GAPIII Containment Certification Scheme (CCS) was endorsed by the WHO Strategic Advisory Group of Experts on Immunization in October 2016.
The following Containment Certification Scheme forms and templates are available to support National Authorities for Containment in the roll-out and implementation of the certification process. All submissions to the Global Certification Commission for the Eradication of Poliomyelitis (GCC) must be made in English.
Guidance to minimize risks for facilities collecting, handling or storing materials potentially infectious for polioviruses (PIM Guidance)
This guidance is intended for ALL facilities but specifically those that could be/don’t know if they are collecting, handling or storing poliovirus. These include facilities that are not purposefully using and manipulating poliovirus for research, diagnostics and or/vaccine production, but rather, might inadvertently be working with the virus through poliovirus potentially infectious material (PV PIM).
The guidance aims to help facilities identify PV PIM and eliminate or minimize risks of handling and storing such material.
|SOP for the identification, destruction or preparation for containment of poliovirus infectious or potentially infectious materials|
|FORM 1: Facility reporting form|
|FORM 2: Containment preparations reporting form|
Looking for every last poliovirus in global sample collections
The global intensification of efforts to appropriately contain polioviruses is critical. To supplement Global Action Plan III for the containment of polioviruses, WHO has published guidance to help facilities identify, destroy, or safely and securely handle and store sample collections potentially infectious for poliovirus.
Dr Mark Pallansch from CDC explains what the guidance means for facilities worldwide.
Poliovirus potentially infectious materials (PV PIM) include fecal, nasopharyngeal, or sewage samples collected in a time and place where wildPolioviruses/vaccine-derived polioviruses (WPV/VDPV), or OPV-derived viruses were circulating or oral polio vaccines (OPV/Sabin) were in use. Facilities with a high probability of storing such materials include those working with rotavirus or other enteric agents, hepatitis viruses, influenza/respiratory viruses, and measles virus. Other facilities could include those conducting nutrition research or environmental facilities.
Poliovirus containment in large-scale polio vaccine production and quality control facilities
This section provides updates on the demand & supply, strategies, policies and recommendations on production and quality control of polio vaccines.
- 16th WHO/UNICEF Consultation with OPV/IPV Manufacturers and National Authorities for Containment, 26 October 2017, Geneva, Switzerland
- 17th WHO/UNICEF Consultation with OPV/IPV Manufacturers and National Authorities for Containment, 9 October 2018, Geneva, Switzerland
- Guidelines for the safe production and quality control of poliomyelitis vaccines