WHO Calls for Expressions of Interest in Developing Sabin-IPV

Safe and affordable inactivated polio vaccine for low-income countries.

One of the strategic priorities of the Global Polio Eradication Initiative is to enable low-income countries to produce Inactivated Polio Vaccine (IPV). To meet this objective,  the World Health Organization is working with academia, government and industry to develop an IPV  based on the non-infectious Sabin virus strain (sIPV). A range of manufacturers and research institutes have active programmes at various stages of development. The development and licensure of IPV produced from Sabin strains aims to reduce the number of manufacturing sites generating high volumes of high titre wild polioviruses for ”traditional” IPV production. Sabin polioviruses pose less of a threat in the event of an intentional or unintentional release from the production facility. This is a particular concern in low-income countries where the transmissibility of polioviruses is high.

Related


Related News

   30/08/2018
By Roland Sutter, Research, Policy and Containment Team, Polio Eradication Department, WHO
   23/07/2018
New study shows fractional dose IPV (fIPV) boosts mucosal immunity in previously OPV-vaccinated children.
   18/04/2018
The global intensification of efforts to appropriately contain polioviruses is critical.
   10/04/2018
How a container village in Belgium is helping us test new polio vaccines.
   26/03/2018
In Pakistan and across the world, the poliovirus surveillance system and laboratory network are critical to eradication efforts.
   02/03/2018
US$ 3.2 million pledged for equipment to help detect the last remaining reservoirs of the virus.